A Template for New Drugs against Alzheimer’s Disease
نویسندگان
چکیده
Alzheimer's disease (AD) is associated with the deposition of β-amyloid (Aβ) plaques in the brain. In this issue, by cleverly processing patient samples, Lu et al. define a novel structural model of Aβ fibrils from AD brain, revealing surprising differences from in vitro fibrils. These findings may lead to structure-specific inhibitors and more selective amyloid-imaging methods.
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ورودعنوان ژورنال:
- Cell
دوره 154 شماره
صفحات -
تاریخ انتشار 2013